I'm using Versus 2k10 and also have a asp.internet 4 application having a sql server db behind it, and that i have 50 deployments from it (50- databases, 50 web application deployments).

Can there be any suggested or standard tool in the market employed for upgrading mass web programs and databases all at one time?

Script it with NAnt... it may pull configs and rewrite they, then deploy all of the files. It may even stop and start IIS.