I am thinking about examining a few of the virus definition files utilized by anti-virus software. These provide free accessibility databases, but all of the a person's I have found to date have been in some type of in-house computer file format (.AVC for Kaspersky Anti-virus, etc).

Can there be any software that utilizes an information format nearer to MySQL, or can these in-house documents be converted?

You could think about ClamAV virus definitions, that are within an open format (as ClamAV is free).

There seems to become some documentation of how to create signatures.