I'm attempting to create a website with Pyramid. This project is require to do something like a Websocket server waiting and responding to Websocket connections. As well as, we must deploy this site on the WSGI-enabled Apache httpd server. Is possible? Steps to make Pyramid support Websocket? Thanks.

You cannot, AFAIK. You should use pyramid_socketio https://github.com/abourget/pyramid_socketio but this dont make use of a frontend.