The majority of the Zend framework books discuss while using framework using the Zend Server. Can you really use Apache rather and when same with there any major drawback?

Yes it's possible. I guess the drawback might be the Web Server isn't instantly set up for you personally, if you do not make use of a WAMP/Light stack like Zend Server.

Obviously you can utilize it with Apache, the only real drawback is you need to configure your atmosphere to be able to make ZF work also to clarify things out Zend Server is definitely an application server not really a web server you are able to think about it as being a Light stack but you may also choose IIS in case your on home windows.